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Leishmania infection alters macrophage and dendritic cell migration in a three-dimensional environment

Frontiers
Background: Leishmaniasis results in a wide spectrum of clinical manifestations, ranging from skin lesions at the site of infection to disseminated lesions...
3 months ago

Ras-oncogenic Drosophila hindgut but not midgut cells use an inflammation-like program to disseminate to distant sites

Taylor & Francis Online
Here we discuss and extent our work on Drosophila melanogaster models of tumorigenesis and tumor cell invasion upon intestinal infection.
143 months ago

Virus-Mediated Cell-Cell Fusion

MDPI
This virus-mediated cell-cell fusion leads to the merge of membrane and cytoplasm contents and formation of multinucleated cells, also called syncytia.
45 months ago

Proteolysis is the most fundamental property of malignancy and its inhibition may be used therapeutically (Review)

Spandidos Publications
Inhibition of proteolysis in cancerous tissue has the ability to attenuate tumor invasion, angiogenesis and migration.
71 months ago

Nitrite Improves Heart Regeneration in Zebrafish | Antioxidants & Redox Signaling

Mary Ann Liebert, Inc.
Aims: Nitrite is reduced to nitric oxide (NO) under physiological and pathological hypoxic conditions to modulate angiogenesis and improve...
58 months ago

HPV16 infection promotes an M2 macrophage phenotype to promote the invasion and metastasis of esophageal squamous cell carcinoma

Springer
High-risk human papillomavirus (HR-HPV) is an important risk factor for esophageal cancer. Macrophages constitute a crucial immune medium...
40 months ago

Generation of membrane structures during phagocytosis and chemotaxis of macrophages: role and regulation of the actin cytoskeleton. - Abstract

Europe PMC
This review will focus on the mechanisms by which macrophages regulate actin polymerization through initial receptor signaling and subsequent Arp2/3 activation.
54 months ago

Tumor-associated macrophages: an effective player of the tumor microenvironment

Frontiers
Cancer progression is primarily caused by interactions between transformed cells and the components of the tumor microenvironment (TME).
8 months ago